Vol. 18 No. 2 (2019)
Original Articles

Can the 6-minute walking test evaluate all patients with respiratory disease?

pdf
  • Marta R. Q. Pimentel,
  • Yves Raphael,
  • Luciane V. B. Nascimento,
  • Rogério Rufino,
  • Adalgisa Maiworm,
  • Kenia M. da Silva,
  • Cláudia Henrique da Costa
Marta R. Q. Pimentel
Respiratory Department, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Yves Raphael
Respiratory Department, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Luciane V. B. Nascimento
Respiratory Department, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Rogério Rufino
Pneumology Department, University Hospital of Rio de Janeiro State University, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Adalgisa Maiworm
Respiratory Department, University Hospital of Rio de Janeiro State University, Rio de Janeiro State University, Rio de Janeiro, Brazil
Kenia M. da Silva
Respiratory Department, University Hospital of Rio de Janeiro State University, Rio de Janeiro State University, Rio de Janeiro, Brazil
Cláudia Henrique da Costa
Respiratory Department, University Hospital of Rio de Janeiro State University, Rio de Janeiro State University, Rio de Janeiro, Brazil
DOI: https://doi.org/10.12957/bjhbs.2019.53507

Published 2020-01-03

Keywords

  • COPD,
  • Lung diseases,
  • Interstitial,
  • Respiratory Function Tests,
  • Walk Test,
  • Walking
    • ...More
    Less

How to Cite

1.
Marta R. Q. Pimentel, Yves Raphael, Luciane V. B. Nascimento, Rogério Rufino, Adalgisa Maiworm, Kenia M. da Silva, Cláudia Henrique da Costa. Can the 6-minute walking test evaluate all patients with respiratory disease?. BJHBS [Internet]. 2020 Jan. 3 [cited 2024 Oct. 11];18(2):136-43. Available from: https://bjhbs.hupe.uerj.br/bjhbs/article/view/122

Copyright (c) 2020 Brazilian Journal of Health and Biomedical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Crossref
Scopus
Google Scholar
Europe PMC

Abstract

Introduction: The 6-minute walking test (6MWT) is a submaximal test used as a clinical indicator of functional capacity in patients with pulmonary disease. However, is has not been defined whether the parameters obtained in the 6MWT are similar in two groups of interstitial lung diseases (ILD), systemic sclerosis (SSc) and idiopathic pulmonary fibrosis (IPF), and what are the differences when compared to patients with chronic obstructive pulmonary disease (COPD). This is a comparative cross-sectional study of 6MWT data, with the inclusion of 32 patients with SSc, 32 with IPF and 50 with COPD. All patients underwent the 6MWT and a respiratory function test. Patients with ILD did not present significant differences when compared with each other. However, when compared to patients with COPD, the ILD group showed greater distance walked (ILD = 404.6 ± 1.09m, COPD = 352.4 ± 10.80m; p = 0.0033) and predicted percentage above 100% (ILD = 113.5 ± 3.72%, COPD = 84.36 ± 4.81%; p <0.0001). Both groups showed a drop in blood oxygen saturation (SaO2) at the end of the test, but the difference between the measured values before and after the 6MWT was more significant in the ILD group (ILD = 10.33 ± 01.09%, COPD = 4.60 ± 12.37%; p <0.0001). The data suggest that, differently from COPD patients, the main parameter to be evaluated during the 6MWT in the ILD group could be the drop in saturation and not the distance walked.

pdf

Metrics

Metrics Loading ...

References

  1. Denton CP. Advances in pathogenesis and treatment of systemic sclerosis. Clin Med. 2016;16(1):55–60.
  2. Cappelli S, Bellando Randone S, Camiciottoli G, et al. Interstitial lung disease in systemic sclerosis: where do we stand? Eur Respir Rev. 2015 Sep;24(137):411–9.
  3. Rubio-Rivas M, Royo C, Simeón CP, Corbella X, et al. Mortality and survival in systemic sclerosis: systematic review and meta-analysis. Semin Arthritis Rheum. 2014 Oct;44(2):208–19.
  4. Sgalla G, Biffi A, Richeldi L. Idiopathic pulmonary fibrosis: Diagnosis, epidemiology and natural history. Respirology. 2016 Apr;21(3):427–37.
  5. Baddini-Martinez J, Baldi BG, Costa CH da, et al. Update on diagnosis and treatment of idiopathic pulmonary fibrosis. J Bras Pneumol. 2015 Sep;41(5):454–66.
  6. Crisafulli E, Torres A. COPD 2017: A Year in Review. COPD: Journal of Chronic Obstructive Pulmonary Disease. 2018;1–5.
  7. Celli BR, MacNee W, Agusti A, et al. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 2004;23(6):932–46.
  8. da Costa CH, da Silva KM, Maiworm A, et al. Can we use the 6-minute step test instead of the 6-minute walking test? An observational study. Physiotherapy. 2017;103(1):48–52.
  9. Rostagno C. 6MWT Predicts Survival Better Than CPET in Patients with Stable Cardiomyopathy. Br J Med Med Res. 2012;2(3):386–95.
  10. van den Hoogen F, Khanna D, Fransen J, et al. 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum. 2013 Nov;65(11):2737–47.
  11. Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med. 2011 Mar 15;183(6):788–824.
  12. ‘Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.’ Vogelmeier CF, Criner GJ, Martinez FJ, et al. Eur Respir J 2017; 49: 1700214. Eur Respir J. 2017;49(6):1750214.
  13. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002 Jul 1;166(1):111–7.
  14. The Borg Rating of Perceived Exertion (RPE) Scale. In: Care of the Obese in Advanced Practice Nursing.
  15. Enright PL, Sherrill DL. Reference Equations for the Six-Minute Walk in Healthy Adults. Am J Respir Crit Care Med. 1998;158(5):1384–7.
  16. Crisafulli E, Iattoni A, Venturelli E, et al. Predicting Walking-Induced Oxygen Desaturations in COPD Patients: A Statistical Model. Respir Care. 2013;58(9):1495–503.
  17. Waatevik M, Johannessen A, Real FG, et al. Oxygen desaturation in 6-min walk test is a risk factor for adverse outcomes in COPD. Eur Respir J. 2016;48(1):82–91.
  18. Godfrey S, Bluestone R, Higgs BE. Lung function and the response to exercise in systemic sclerosis. Thorax. 1969;24(4):427–34.
  19. Park JH, Jegal Y, Shim TS, et al. Hypoxemia and arrhythmia during daily activities and six-minute walk test in fibrotic interstitial lung diseases. J Korean Med Sci. 2011 Mar;26(3):372–8.
  20. Buch MH, Denton CP, Furst DE, et al. Submaximal exercise testing in the assessment of interstitial lung disease secondary to systemic sclerosis: reproducibility and correlations of the 6-min walk test. Ann Rheum Dis. 2007 Feb;66(2):169–73.
  21. Lederer DJ, Arcasoy SM, Wilt JS, et al. Six-minute-walk distance predicts waiting list survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2006 Sep 15;174(6):659–64.
  22. Manali ED, Lyberopoulos P, Triantafillidou C, et al. MRC chronic Dyspnea Scale: Relationships with cardiopulmonary exercise testing and 6-minute walk test in idiopathic pulmonary fibrosis patients: a prospective study. BMC Pulm Med. 2010 May 28;10:32.
  23. Verma G, Marras T, Chowdhury N, et al. Health-related quality of life and 6 min walk distance in patients with idiopathic pulmonary fibrosis. Can Respir J. 2011 Sep;18(5):283–7.
  24. Schoindre Y, Meune C, Dinh-Xuan AT, et al. Lack of specificity of the 6-minute walk test as an outcome measure for patients with systemic sclerosis. J Rheumatol. 2009 Jul;36(7):1481–5.
  25. Caminati A, Bianchi A, Cassandro R, et al. Walking distance on 6-MWT is a prognostic factor in idiopathic pulmonary fibrosis. Respir Med. 2009 Jan;103(1):117–23.
  26. Flaherty KR, Andrei A-C, Murray S, et al. Idiopathic pulmonary fibrosis: prognostic value of changes in physiology and six-minute-walk test. Am J Respir Crit Care Med. 2006 Oct 1;174(7):803–9.
  27. Rasekaba T, Lee AL, Naughton MT, et al. The six-minute walk test: a useful metric for the cardiopulmonary patient. Intern Med J. 2009 Aug;39(8):495–501.
  28. Villalba WO, Sampaio-Barros PD, Pereira MC, et al. Six-minute walk test for the evaluation of pulmonary disease severity in scleroderma patients. Chest. 2007 Jan;131(1):217–22.

Most read articles by the same author(s)